Does the use of oxytocin in a pulsatile fashion (intermittent boluses), when compared to the use of continuous oxytocin, for the commencement and/or assistance of labour, result in a reduction in the number of caesarean sections that are required?
Phase 4
- Conditions
- abour (induction of)Labour (induction of)Reproductive Health and Childbirth - Antenatal careReproductive Health and Childbirth - Childbirth and postnatal careReproductive Health and Childbirth - Fetal medicine and complications of pregnancy
- Registration Number
- ACTRN12619000588190
- Lead Sponsor
- Darren Lowen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Stopped early
- Sex
- Female
- Target Recruitment
- 200
Inclusion Criteria
Any of the indications for induction of labour including the following:
Diabetes (Type I, Type II, gestational diabetes, which is poorly controlled)
Hypertension
Pre-elcampsia
Prolonged pregnancy defined as being greater than 41 weeks
Term prolonged rupture of membrane
Reduced fetal movements +/- non-reassuring CTG
Past history of fetal death in utero
Chorioamnionitis
Low PAPP-A
Advanced maternal age (defined as greater than or equal to 40 years of age)
Blood group isoimmunisation
Suspected intrauterine growth restriction
Exclusion Criteria
Age less than 18 years
Women who do not have the mental and/or legal capacity to consent
Fetal presentation other than cephalic
Gestational age < 37 weeks
Multiple pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is the incidence of emergency (unplanned) caesarean sections, as determined from the patient's medical record and as described by the treating obstetrician[The primary timepoint is the birth of the fetus. ]
- Secondary Outcome Measures
Name Time Method