Effects of eplerenone on cardiovascular and metabolic disorders in patients with primary aldosteronism
Not Applicable
- Conditions
- essential hypertension, primary aldosteronism
- Registration Number
- JPRN-UMIN000004581
- Lead Sponsor
- Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1. pregnant or lactating women 2. malignant hyperension 3. secondary hypertension except for primary aldosteronism 4. diabetes mellitus patients with unstable glycemic control whose HbA1c is more than 8%, or complicated with diabetic nephropathy more than stage 2. 5. patients whose serum triglycemide is more than 400mg/dL 6. patient who is intolerate or allergic agiansts eplerenone and amlogipine 7. patient whose renal function (estimated GFR) is less than 50mL/min. 8. patient whose serum potassium level is more than 5.0mEq/L 9. patinet who sufferd from severe hepatic injury
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method