Efficacy of Intravenous versus Perineural Magnesium Sulfate as an adjunct to Ropivacaine in Axillary Plexus Block: A Randomized Controlled Double Blind Trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 123
- 试验地点
- 1
- 主要终点
- Sensory blockade duration
研究概览
简要总结
In axillary brachial plexus block, located anaesthetic agents provide reliable anaesthesia and analgesia for forearm and hand surgeries. The effect of the block can be prolonged and improved with the use of various adjuvants. Magnesium sulfate with both perineural and intravenous routes showing potential benefit, has not been compared directly in this setting. This study will evaluate whether intravenous or perineural magnesium sulfate, when used as an adjuvant to 0.5% ropivacaine increases the duration and quality of block and improves post operative analgesia and patient satisfaction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anaesthesiologists physical status (ASA) I-III.
- •Patients undergoing forearm and hand surgeries.
排除标准
- •Patients with allergy to Ropivacaine and Magnesium sulfate.
- •Coagulopathy or local infection at the injection site.
结局指标
主要结局
Sensory blockade duration
时间窗: Assessed from time of completion of block until complete return of sensation, recorded in minutes.
次要结局
- Sensory blockade onset(Onset time of sensory blockade in minutes.)
- Motor blockade onset(Onset time of motor blockade in minutes.)
- Motor blockade duration(Duration of motor blockade in minutes.)
- Post operative analgesia duration(Total duration of post operative analgesia in hours.)
- Total opioid consumption in mg(24 hours.)
- Post operative VAS score(0, 3, 6, 9, 12 and 24 hours.)
- Patient satisfaction with Likert scale(24hours postoperatively.)
研究者
Dr Reetu Arora
Kalinga Institute of Medical Sciences