跳至主要内容
临床试验/NCT06283251
NCT06283251
招募中
不适用

Pilot Randomized Pediatric RISE (Resource Intervention to Support Equity) Feasibility Study

Dana-Farber Cancer Institute8 个研究点 分布在 1 个国家目标入组 40 人2024年5月15日

概览

阶段
不适用
干预措施
PediRISE Resource Program
疾病 / 适应症
Pediatric Cancer
发起方
Dana-Farber Cancer Institute
入组人数
40
试验地点
8
主要终点
Participant Consent Rate
状态
招募中
最后更新
2个月前

概览

简要总结

The goal of this research study is to learn whether investigators can successfully give the PediRISE program to families-in other words, whether most families are interested in participating in a study about the PediRISE program, including a 50-50 chance of receiving standard usual care, and a 50-50 chance of receiving the PediRISE support program.

The names of the study groups in this research study are:

  • PediRISE Program Group
  • Usual Care Group

详细描述

This is a pilot, multi-center, randomized research study for the feasibility of the administration of the PediRISE program among 40 poverty exposed children with (1) a new diagnosis of childhood cancer at DFCI and Columbia University and among poverty-exposed families with a child with cancer and (2) receiving hematopoietic stem cell transplant (HSCT) at DFCI, Columbia University, or the University of California - San Francisco (UCSF). Randomization means there is an equal chance of being assigned to the PediRISE Program Group or the Usual Care Group. Study procedures include screening for eligibility, study visits, and completion of surveys and questionnaires. Participation in this study will last for about 6-months. It is expected that about 40 pediatric participants with parents/guardians will take part in this research study. This study is being supported by grants from the American Cancer Society and the Children's Cancer Research Fund.

注册库
clinicaltrials.gov
开始日期
2024年5月15日
结束日期
2027年6月30日
最后更新
2个月前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Principal Investigator
主要研究者

Kira Bona, MD, MPH

Principal Investigator

Dana-Farber Cancer Institute

入排标准

入选标准

  • Cohort 1: Poverty-exposed children with cancer receiving front-line cancer-directed therapy
  • Child diagnosed with de novo cancer
  • Child has established care at a study site and initiated cancer directed therapy in the prior 2-months
  • Child planned to receive at least 4-months of cancer-directed therapy at study site from time of diagnosis per initial cancer treatment plan
  • Child is \<18 years at time of enrollment
  • Parent/guardian screened positive for self-reported low-income (\<200% FPL)
  • Family primary residence in CA, CT, MA, ME, NH, NJ, NY or RI
  • Provider approval for permission to approach
  • Cohort 2: Poverty-exposed children with cancer undergoing HSCT
  • Child undergoing allogeneic HSCT for treatment of cancer

排除标准

  • Cohort 1: Poverty-exposed children with cancer receiving front-line cancer-directed therapy
  • Planned transfer of child to a non-DFCI or non-Columbia facility for cancer-directed therapy
  • Foreign national family receiving care as an Embassy-pay patient
  • Child is enrolled on embedded correlative health equity aims of open or upcoming clinical drug trials which are powered on descriptive parent-reported poverty data (e.g. AALL1731, DFCI 25-001). Co-enrollment on a poverty intervention study would confound the specified endpoints of these open trial correlative studies
  • Child or household member receiving SSI
  • Cohort 2: Poverty-exposed children with cancer undergoing HSCT
  • Planned transfer of child to a non-DFCI, non-Columbia, or non UCSF facility for cancer-directed therapy
  • Foreign national family receiving care as an Embassy-pay patient
  • Child is enrolled on embedded correlative health equity aims of open or upcoming clinical drug trials which are powered on descriptive parent-reported poverty data (e.g. AALL1731, DFCI 25-001). Co-enrollment on a poverty intervention study would confound the specified endpoints of these open trial correlative studies
  • Child previously received RISE intervention

研究组 & 干预措施

PediRISE Program Group

Participants will be randomized in a 1:1 fashion and will be stratified by site. Participant parents will complete: * Baseline survey in-person, by telephone, or virtually. * PediRISE program orientation with study team member, in-person or virtual. * Optional meeting with certified benefits counselor. * Receive fixed funds twice a month for 6 months. * Standard supportive care from social worker and/or resource specialist to identify and discuss available resources. * End of study survey.

干预措施: PediRISE Resource Program

Usual Care Group

Participants will be randomized in a 1:1 fashion and will be stratified by site. Participant parents will complete: * Baseline survey in-person, by telephone, or virtually, and orientation with study team member. * Standard supportive care from social worker and/or resource specialist to identify and discuss available resources. * End of study survey.

结局指标

主要结局

Participant Consent Rate

时间窗: 1 Day

The proportion of eligible participants who provide informed consent to participate in the randomized guaranteed income intervention.

Participant Attrition Rate

时间窗: At 6 months

The proportion of participants who withdraw from the study, are lost to follow-up, or otherwise do not complete the assigned study procedures.

研究点 (8)

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