The Investigation on the Effect of Boswellia resin Extract on Plasma Levels of inflammatory factors in Patients with Alzheimer’s disease
Not Applicable
- Conditions
- Alzheimer's disease.Alzheimer's disease
- Registration Number
- IRCT20170315033086N3
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Positive DSM-IV
Positive NINCDS/ ADRDA
MMSE includes 10-26
No family history of Alzheimer's disease
Hamilton test is less than or equal to 12 in 17th item
Memory score below 1
BMI includes 18-25
No background of peptic ulcer,surgery of digesting system, or haemorrhage of digesting system
No taking NSAIDs or systemic corticosteroid during previous two months
No alcohol consumption
Age range is 55-85
Exclusion Criteria
Turning to negative DSM-IV during Boswellia resin extract period
Turning to positive NINCDS/ ADRDA during Boswellia resin extract period
Acute viral, bacterial or severe infectious disease during research
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pro- and anti-inflammatory factors. Timepoint: At the recruitment day and after intervention period. Method of measurement: ELISA assay kit.;MMSE (Mini-Mental State Examination) test. Timepoint: At the recruitment day and after intervention period. Method of measurement: MMSE questionnaire (contained 30 question point involved evaluation of attention and calculation, recall, ability to follow simple commands and orientation).
- Secondary Outcome Measures
Name Time Method