Dexmedetomidine Versus Propofol for Sedation in Stereotactic Brain Biopsy
Phase 4
Completed
- Conditions
- Adverse Effects in the Therapeutic Use of Other and Unspecified Agents Primarily Acting on the Respiratory System
- Interventions
- Drug: dexmedetomidine/ propofol
- Registration Number
- NCT03375385
- Lead Sponsor
- Ain Shams University
- Brief Summary
Pre-operative anxiety leads to higher sympathetic stimulation. Propofol in the main drug used during interventional or imaging techniques that need sedation. Also, dexmedetomidine causes sedation, analgesia, sympatholytic properties, without respiratory depression.In stereotactic brain biopsy; patient discomfort due to drilling a hole through the skull and the advancement of the biopsy needle make the patient in need for good sedation and analgesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
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Exclusion Criteria
Not provided
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Hemodynamic parameters dexmedetomidine/ propofol - Ramsay sedation score dexmedetomidine/ propofol - Intraoperative side effects dexmedetomidine/ propofol - recovery of sedation dexmedetomidine/ propofol -
- Primary Outcome Measures
Name Time Method the sedation characteristics 4 hours Ramsay sedation score
- Secondary Outcome Measures
Name Time Method