MEASUREMENT OF LEFT HEART VOLUME DURING SURGERY USING ECHOCARDIOGRAPHY AND COMPARING THEM WITH GOLD STANDARD RADIOLOGICAL IMAGING MEASUREMENTS

Not Applicable

Conditions: Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Registration Number: CTRI/2019/07/020182

Lead Sponsor: Sree Chitra Tirunal Institute for Medical Sciences and Technology

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. Adult patients with coronary artery disease undergoing elective coronary artery bypass grafting (CABG) without repair or replacement of other valves.

2. Patient operated for CABG first time.

Exclusion Criteria

1. Patients below 18 years of age and > 70 years of age

2. Inadequate imaging of LV to interpret the results on CMR, intraoperative 2D TEE, or RT-3D TEE

3. Patients with dilated heart in whom we anticipate inadequate 3D TEE imaging

4. Patients with orthopnea

5. Patients not in sinus rhythm

6. More than mild mitral or aortic stenosis

7. More than mild pulmonary or tricuspid regurgitation

8. Concomitant repair or replacement of other valves

9. Patients having atrial septal defect, ventricular septal defect, patent ductus arteriosus or any significant pathology that will cause intra or extra cardiac shunting of blood

10. Re-do CABG

11. Incompatibility with cardiac MRI - patients having MRI incompatible implants or severe claustrophobia or patient unable to lie in the MRI gantry

12. Contraindication to TEE probe placement

13. Patient refusing to participate in the project

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To quantify and correlate the LV end-diastolic volume and LV end-systolic volume measured with intraoperative realtime three dimensional transesophageal echocardiography (RT-3D TEE) with those obtained from cardiac magnetic resonance (CMR) imaging <br/ ><br> 2. To compare and correlate the left ventricle ejection fraction (LVEF) obtained by intraoperative RT-3D TEE with those obtained from CMRTimepoint: Not applicable for this study as the outcome measures are evaluated during the pre-operative and intra-operative period and no further follow up is required

Secondary Outcome Measures

Name	Time	Method
1. To quantify and correlate the LV end-diastolic volume and LV end-systolic volume measured with intraoperative 2D TEE with those obtained from CMR imaging <br/ ><br> 2. To compare and correlate the LVEF obtained by intraoperative 2DE with CMRTimepoint: Not applicable for this study as the outcome measures are evaluated during the pre-operative and intra-operative period and no further follow up is required