Clinical evaluation of Mashiningan and Daiokanzoto for the relief of constipation in Parkinson's disease

Not Applicable

• Conditions: Constipation of Parkinson' s disease patients

• Registration Number: JPRN-UMIN000013879
• Lead Sponsor: Division of Oriental Medicine Center for Community Medicine Jichi Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-06-01
• Study Completion: 2018-03-20
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

1) Pregnant women or nursing mothers 2) Patients with apparent obstructions (such as tumors or hernias) in the intestinal tract 3) Patients with drug-induced constipation 4) Patients with known megacolon/megarectum or intestinal pseudo-obstruction 5) Patients who have undergone prior gastrointestinal surgery or abdominal surgery during the 3 months prior to the start of the study 6) Patients with significant cardiac, hepatic, pulmonary, renal, or mental diseases 7) Patients with severe clinical findings or abnormal laboratory (hematology/urinalysis) findings 8) Patients with uncontrolled hypertension, hyperaldosteronism, hypokalemia, or myopathy 9) Patients who may not comply with this research study protocol 10) Patients diagnosed with cancer within 5 years from the start of the study (except for carcinoma in situ) 11) Patients with constipation that is controlled through treatment with Mashiningan or Daiokanzoto prior to the start of this study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Constipation assessment scale

Secondary Outcome Measures

Name	Time	Method
1) Bristol stool scale 2) Presence or absence of adverse effects 3) Other individual outcomes, obtained from responses to the questionnaire(Abdominal bloating, stool frequency, sensation of incomplete evacuation, straining, etc.)