Effect of Periodontal Treatment on Salivary Biomarkers.
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 主要终点
- Whole saliva & translocator protein (TSPO)
研究概览
简要总结
The investigators plan to recruit 40 healthy patients referred to the unit of Periodontology, diagnosed with generalized moderate - severe chronic periodontitis.
treatment will include 4 - 6 sessions of scaling + root planning, oral hygiene instructions and motivation.
Whole saliva will be collected at intake and 8 - 14 weeks post periodontal treatment.
Saliva will be analyzed for trans locator protein. Study hypothesis: Periodontal treatment has an affect on saliva components.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy patients
- •moderate - sever chronic periodontitis
排除标准
- •systemic disease
- •pregnancy
- •subjects under the age of 18
结局指标
主要结局
Whole saliva & translocator protein (TSPO)
时间窗: Intake of patients than 8 - 12 weeks after periodontal treatment (scaling & root planning)
Change in whole saliva \& translocator protein (TSPO) post periodontal treatment
次要结局
- Periodontal measurements (periodontal pocket depth, bleeding on probing & clinical attachment level)(Intake 8 - 12 weeks post periodontal treatment (scaling & root planning))
研究者
Eran Front
Unit of Periodontology - Department of Oral and Maxillofacial surgery
The Baruch Padeh Medical Center, Poriya