â??A Comparative Clinical Study OfYashtimadhu Ghrita And Lignocaine-Nifedipine Ointment In The Management Of Parikartika (Acute Fissure- In- Ano).â??
Phase 1
- Conditions
- Health Condition 1: null- PARIKARTIKA ( ACUTE FISSURE IN ANO)
- Registration Number
- CTRI/2016/11/007496
- Lead Sponsor
- IPGT AND RA GAU JAMNAGAR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1.Patients of Parikartika (Acute fissure-in-ano) having duration less than 12 weeks.
2.Controlled cases of Diabetese mallitus or Hypertension
Exclusion Criteria
1.Fissure-in-ano having duration- more than 12 weeks.
2.Patient below 17 & above 70 years of age.
3.Patient suffering from malignancy.
4.Patient suffering from HIV, VDRL, Hepatitis-B, T.B.
5.Fissure-in-ano associated with piles & fistula.
6.Multiple fissure in ano
7.Uncontrolled cases of Diabetes Mellitus and Hypertension
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ASSESSMENT WILL BE DONE ON THE BASIS OF SPECIALLY PREPARED PERFORMA FOR ASSESSING RELIEF IN SIGN AND SYMPTOMS BY SCORING PATTERNTimepoint: ASSESSMENT WILL BE DONE ON THE BASIS OF SPECIALLY PREPARED PERFORMA FOR ASSESSING RELIEF IN SIGN AND SYMPTOMS BY SCORING PATTER
- Secondary Outcome Measures
Name Time Method 1 MONTHTimepoint: 1 MONTH
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Yashtimadhu Ghrita's efficacy in acute fissure-in-ano compared to lignocaine-nifedipine ointment?
How does lignocaine-nifedipine combination therapy compare to standard-of-care calcium channel blockers for anal fissure management?
Which inflammatory biomarkers correlate with treatment response in acute fissure-in-ano patients using Ayurvedic or pharmacologic interventions?
What adverse event profiles are reported for Yashtimadhu Ghrita versus lignocaine-nifedipine in phase I anal fissure trials?
Are there alternative Ayurvedic formulations or drug combinations targeting anal fissure pathophysiology similar to Yashtimadhu Ghrita and lignocaine-nifedipine?