Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to Ketamine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- analgesic efficacy
研究概览
简要总结
This is a randomised, controlled, double blinded study comparing in the postoperative setting the analgesic efficacy, the safety and the cost in two groups of patients receiving in the postanesthesia care unit either intravenous morphine titration alone or intravenous morphine titration combined to ketamine.
详细描述
Randomised, controlled, double blinded study comparing in the postoperative setting the analgesic efficacy, the safety and the cost in two groups of patients receiving in the postanesthesia care unit either intravenous morphine titration alone or intravenous morphine titration combined to ketamine
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 yrs
- •scheduled surgery
- •General anesthesia
- •ASA I to III
- •Able to use a VAS
- •No psychological disorders, able to speak french
排除标准
- •Age < 18 yrs
- •Locoregional anesthesia or analgesia
- •Allergia to morphine or ketamine
- •Morphine or ketamine contraindication
- •Pregnancy or breast-feeding
研究组 & 干预措施
treatment
intravenous morphine titration combined to ketamine
干预措施: Ketamine (Drug)
placebo
morphine titration alone
干预措施: Ketamine (Drug)
结局指标
主要结局
analgesic efficacy
时间窗: 24 h
the analgesic efficacy, in two groups of patients recevieving in the postanesthesia care unit either intravenous morphine titration alone or intravenous morphine titration combined to ketamine
次要结局
未报告次要终点