Clinical and radiographic evaluation of biodentine and low level laser therapy for full pulpotomy in permanent teeth- A randomized controlled trial

This study is a randomized controlled trial evaluating the clinical and radiographic symptoms in full pulpotomy with and without photobiomodulation using low level laser therapy at 3 months and 6 months interval. Following the inclusion and exclusion criteria and obtaining consent from the patients, they will be divided into two groups. in both the groups, caries will be excavated and coronal access will be made under rubber dam isolation.  Primary hemostasis is obtained using 2.5% sodium hypochlorite within 5 minutes. In Group A, 2-3mm thick layer of Biodentine (Septodont, France) is mixed and placed according to manufacturer’s instruction, followed by a layer of resin modified glass ionomer cement and permanent restoration using composite. In Group B, the root canal orifice will be exposed to Diode laser (SiroLaser Blue, Densply Sirona) of 660nm in continuous mode of application for approximately 60 seconds which will be kept at 1-2mm distance at 200 mW power. Both  the operator and the patient will be wearing protective eyewear during the laser application. The rest of the procedures are the same as Group A. Patients will be assessed for clinical symptoms after 24 hours and after 1 week. The primary outcome is the clinical and radiographic analysis which will be done at 3 months and 6 months interval. The patients will be clinically assessed for sensitivity, pain, tender on percussion, draining sinus, swelling and mobility. The radiographic changes such as periodontal ligament space widening, periapical radiolucency, furcal lesion, internal and external root resorption will be assessed. Success will be determined by the absence of symptoms. If failure is diagnose, the tooth will be endodontically treated.