Serum Preptin and Amylin Levels in Polycystic Ovary Syndrome Patients

Completed

• Conditions: Polycystic Ovary Syndrome
• Interventions: Diagnostic Test: preptin and amylin level

• Registration Number: NCT03587415
• Lead Sponsor: Recep Tayyip Erdogan University Training and Research Hospital

Brief Summary

Preptin and amylin are pancreatic hormones which participate in glucose homeostasis. This study aims to evaluate how serum preptin and amylin levels are altered in polycystic ovary syndrome (PCOS) patients and healthy women based on BMI groups .

Detailed Description

Materials and Methods: This is a cross-sectional review of 40 PCOS patients and 40 healthy women who were matched with respect to BMI (\<25 kg/m2 and ≥25 kg/m2).

Study Timeline

• Study Start: 2017-06-28
• Primary Completion: 2017-11-30
• Study Completion: 2017-12-07
• Study First Submitted: 2018-06-12
• Status Verified: 2018-07
• Study First Submitted QC: 2018-07-13
• Last Update Submitted: 2018-07-13
• Study First Posted: 2018-07-16
• Last Update Posted: 2018-07-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

the patients with PCOS

Exclusion Criteria

Cushing's syndrome 21-hydroxylase deficiency Congenital adrenal hyperplasia Thyroid dysfunction Hyperprolactinemia Diabetes Chronic cardiovascular Hepatic, renal, and hematologic diseases Malignancies Using oral contraceptives, anti-androgens, glucocorticoids, anti-hypertensives, anti-diabetics, calcium supplements and anti-obesity drugs and those who smoke or consume alcohol

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Healty groups	preptin and amylin level	These women who have reguler menstrual cycle, no akne or hirsutism, we will use their boold samples
Polycyctic ovary sendrome (PCOS)	preptin and amylin level	these women who have PCOS, we will use their blood samples

Primary Outcome Measures

Name	Time	Method
Serum Preptin and Amylin Levels with Respect to Body Mass Index in Polycystic Ovary Syndrome Patients	six months	Serum Preptin and Amylin Levels will compare between groups

Trial Locations

Locations (1)

Recep Tayyip Erdogan University; 🇹🇷 Rize, Turkey