Automatic versus manual oxygen titration in adults admitted to hospital with or without COVID-19: a randomised controlled trial comparing time spent with oxygen levels within a target range

Fisher and Paykel Healthcare0 个研究点目标入组 62 人开始时间: 2022年3月17日最近更新: 2023年6月13日

适应症

试验速览

暂无简介。

•Supplemental oxygen requirement >= 2L/min nasal prongs for those with a target SpO2 of 92-96% appropriate (not at risk of hypercapnic respiratory failure)
•Supplemental oxygen requirement >= 1L/min nasal prongs for those with a target SpO2 of 88-92% appropriate (risk of hypercapnic respiratory failure)
•Requirement for NHF/CPAP/ Bi-level therapy as deemed appropriate by the patient’s treating clinician
•Expected duration of oxygen therapy >9 hours
•Measured for at least 8 hours of the initial 9 hour study period

•Age < 18
•Imminent (within 1 hour) need for invasive mechanical ventilation or intensive care unit support (based on treating clinician assessment)
•Haemodynamic instability (systolic blood pressure <90mmHg or requirement for vasopressor or inotropic support)
•Patient receiving end of life care
•Risk of barotrauma, as assessed by the investigator
•Nasal or facial conditions precluding use of NHF, CPAP or Bi-level
•Pregnancy or breastfeeding
•Cognitive impairment or impaired consciousness precluding informed consent
•Any other condition which, at the investigator’s discretion, is believed may present a safety risk or impact the feasibility of the study or the study results

发起方

Fisher and Paykel Healthcare