The effect of adenosine in cardioplegic solutio

Phase 2

Recruiting

• Conditions: Mitral valve surgery.; Mitral (valve) failure; I05.8

• Registration Number: IRCT2016061428454N1
• Lead Sponsor: Rajaee hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 December 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

patients' willingness to participate in research; written informed consent; all of patients with mitral valve disease. Exclusion criteria: patients with aortic valve disease; pulmonary disease; two valves diseases; coronary heart disease; liver disease; kidney disease; lung disease; high blood pressure; diabetes; asthma; heart surgery; cardiac output less than 30%; history of adenosine-sensitivity and all the patients had a previous surgical history.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TNF-a. Timepoint: Before and after the intervention. Method of measurement: Laboratory analysis of blood samples.

Secondary Outcome Measures

Name	Time	Method
Hemodynamic parameters. Timepoint: 1. Basic 2-15 minutes after CPB 3-6 hours after CPB 4-24 hours after CPB. Method of measurement: Heart rhythm ECG, Blood pressure by artelain, CVP transducer dome.