What brain waves indicate conscious response during anaesthesia?

Not Applicable

Recruiting

• Conditions: AnaesthesiaAwareness; Anaesthesia; Awareness; Anaesthesiology - Other anaesthesiology; Neurological - Studies of the normal brain and nervous system

• Registration Number: ACTRN12617000533392
• Lead Sponsor: Waikato Hospital Dept of Anaesthesia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-04-12
• Last Update Posted: 13 September 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Adults undergoing airway surgery at Waikato Hospital

Exclusion Criteria

Inability to provide informed consent
Inability to follow commands appropriately preoperatively

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
EEG markers. Corresponding multichannel EEG epochs will be analysed for spectral measures, connectivity measures, entropy and other putative markers of consciousness/unconsciousness[EEG recordings will be continuous from induction of anaesthesia to emergence from anaesthesia. Specific epochs of interest will include: <br>Loss of consciousness<br>Surgical stimulation<br>Episodes of spontaneous movement<br>Return of consciousness <br>]

Secondary Outcome Measures

Name	Time	Method
Behavioural response to verbal command by an observer ('X (patient's name), if you can hear me, squeeze my hand') assessed by observer noting whether or not their hand was squeezed[Verbal commands will be given throughout the induction of anaesthesia (every 30 seconds), maintenance(every 5 minutes) and emergence of anaesthesia (every 30 seconds). ];Reflex motor responses to painful stimuli[There will be continuous observation for movements which could occur following any painful stimulus; an observer will record the time and a description of any movements observed<br>];Implicit memory of verbal cues given at time of insertion of operating laryngoscope measured using the 2 Alternative Forced Choice Method[In the post-anaesthesia care unit];Composite autonomic responses (heart rate variability (from continuous ECG recordings) and galvanic skin responses (continuous sensor))[Continuous monitoring from induction of anaesthesia to emergence from anaesthesia]