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Secondary Prevention of Dug-related Problems Through Digital Health

Not Applicable
Conditions
Drug-Related Problems
Interventions
Device: MyPlan digital health platform
Other: Satndard care
Registration Number
NCT04841863
Lead Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Brief Summary

The purpose of this study is to evaluate the clinical impact of a program for the secondary prevention of drug-realted problems (DRP) focused on the patient empowerment through Digital Health in patients who visit the Emergency Department (ED) of the Hospital de la Santa Creu i Sant Pau (HSCiSP) for a health problem related to medication in terms of readmissions, revisits and quality of life.

Detailed Description

After being infomed about the estudy and potential risks, all patients who meet the eligibility requirements and giving written informed consent, will be randomized.

The project is structured in two consecutive phases.

1. st Phase: 3-month randomized pilot study. Patients will be randomized with a 1:1 distribution to be included in the Drug Code Active Patient or DCAP (intervention group) or to receive usual care (control group). The pilot study will confirm whether the proposed methodology is feasible to implement it on a large scale, as well as providing the information necessary to calculate the sample of patients according to the main objective of the study.

2. nd Phase: Randomized clinical trial lasting 18 months (6 of which will be recruitment and 12 months follow-up) following the methodology described for the pilot in a larger sample of patients until the calculated sample size is achieved.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Age greater than or equal to 18 years.
  • Visit ED for a DRP caused bu a drug of the ATC groups A, B, C or N.
  • Be independent for activities of daily living (equivalent to Barthel 100).
  • Have a Chalson Comorbidity Index 2 <= 3.
  • Not present cognitive impairment.
  • Be directly responsible for pharmacotherapy.
  • Have a mobile device compatible with the MyPlan mobile application and access to Wi-Fi or mobile data, enabling the use of the technology platform from home.
Exclusion Criteria
  • Important language barrier.
  • Impossibility of carrying out the necessary questionnaires or interviews defined in the methods of this study.
  • Mental pathology that makes the autonomous use of technology impossible or that represents a safety problem for the patient according to clinical criteria.
  • Patients not residing in the territory who cannot be followed-up later.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Drug Code Active Patient o DCAPMyPlan digital health platformInclusion in the active group involves the use of MyPlan digital health tool that aims to improve clinical-patient communication, enahnce patient empowerment, improve early detection of side effects and allows professionals to individualize interventions. Patients will receive follow-up by videoconference 48 hours after discharge and in the phase II, at 6 and 12 months after discharge.
Standard careSatndard careInclusion in the control group do not involves the use of MyPlan digital health tool. Patients will receive the standard of care. Patients will receive follow-up by videoconference 48 hours after discharge and in the phase II, at 6 and 12 months after discharge.
Primary Outcome Measures
NameTimeMethod
Clinical impact of a digitial health tool for secondary prevention of DRP focused on patient empowerment.Baseline, 48h after discharge, 6-month and 12-month after discharge (in phase II, Clinical Trial)

Change in clinical impact during the follow-up time will be evaluated in terms of number of readmissions, number of revisits and quality of life (based on the result obtained in the EQ-5D-3L51 questionnaire)

Secondary Outcome Measures
NameTimeMethod
Identify which groups of drugs are more frequently associated to DRPBaseline

Using ATC group classification

Change in the patient therapeutic adherenceBaseline, 48h after discharge, 6-month and 12-month after discharge (in phase II, Clinical Trial)

Active days on the MyPlan platform, functionalities used, number of queries made through platform messaging

Change in the quality of life of patients in the active groupBaseline, 6-month and 12-month after discharge (in phase II, Clinical Trial)

Using the EQ-5D-3L51 questionnaire

Measure the usability and satisfaction of patients, caregivers and professionals of the MyPlan digital health tool12-month after discharge (in phase II, Clinical Trial)

Using the TrilemaSalud questionnaire

Identify, classify, and quantify DRP that cause urgent care in a tertiary hospital in this patient population.Baseline

Type of DRP that promotes ED visits characterized according to the three dimensions of the Third Consensus of Granada (Need, Effectiveness and Safety)

Identify risk factors for ED visits related to DRPBaseline

Age, sex, social and familiar environment, blood presure (mmHg), heart frequency (bpm), Hb1Ac (%), pain (visual analog scale), weight (kg) and height (cm), chronic kidney disease, number of drugs at admission and at discharge, number of chronic health problems.

Mesure therapeutic complexityBaseline

Using patient Medication Regimen Complexity Index (pMRCI-S) questionnaire

Identify predictive factors of a greater capacity for digital empowerment.Baseline

Using the CAMBADOS questionnaire

Trial Locations

Locations (1)

Hospital de la Santa Creu i Sant Pau

🇪🇸

Barcelona, Spain

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