Regulation of HIIT Combined with IET on Vascular Function in Young Women with Normal Weight Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Intima-Media Thickness (IMT)
研究概览
简要总结
Comparison of the effects of combined IET with HIIT and HIIT on vascular function in young NWO women.
详细描述
This is a randomized clinical trial of single-blind with 3 arms (control group , HIIT group and IET with HIIT group), in which a pre-treatment-posttest design has been used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female, aged between 18 and 30 years old;
- •BMI between 18.5 and 24.9 kg/m2 with a BF% > 30% (normal weight obesity determination criteria);
- •exercise capacity to complete the exercise programme.
排除标准
- •Acute or chronic musculoskeletal disorders, cardiovascular diseases, etc. that prevented training;
- •other diseases (such as diabetes, etc.) that had a great impact on physical condition;
- •bad habits (such as smoking, drinking, etc.);
- •and unstable body weight (up and down fluctuations of more than 2.5 kg) in the 3 months before the experiment.
研究组 & 干预措施
HIIT group
干预措施: HIIT (Behavioral)
HIIT combined IET group
干预措施: HIIT combined IET (Behavioral)
Control group
结局指标
主要结局
Intima-Media Thickness (IMT)
时间窗: 8 weeks
The subjects were required to sit still for 5～10 minutes before the test, and the carotid artery structural and functional parameters were recorded using a GE vivid 7 colour ultrasound instrument from the United States as follows: the subjects were required to lie in the supine position, and the probe was used to sweep longitudinally along the outer edge of the sternocleidomastoid muscle, and the maximal Intima-media thickness (IMT) was measured. Changes in Intima media thickness before and after intervention.
Flow-Mediated Dilation (FMD)
时间窗: 8 weeks
Vascular endothelial function was measured with a Japanese-made UNEX EF vascular endothelial function tester. Pressure was applied on top of the resting blood pressure and the ischaemic process was performed for 5 min. At the end of the ischaemic process, the pressure band was removed and flow-mediated dilation (FMD) of the brachial artery was calculated. Changes in Flow-mediated dilation before and after Intervention
次要结局
- Body Mass Index (BMI)(8 weeks)
- Blood Pressure (BP)(8 weeks)
- Pulse Wave Velocity (PWV) and ankle brachial index (ABI)(8 weeks)
- Volume Oxygen Maximum (VO2max)(8 weeks)
- Body Composition Indicators(8 weeks)