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Efficacy and Safety of Tacrolimus as Secondline Therapy for Patients With Autoimmune Hepatitis Pilot Study

Not Applicable
Conditions
Autoimmune Hepatitis
Registration Number
JPRN-UMIN000030743
Lead Sponsor
Hiroshima University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
5
Inclusion Criteria

Not provided

Exclusion Criteria

1.Liver cirrhosis 2.HBV , HCV, PBC, NASH 3.Arrergy of Tacrolimus 4.Arrergy of ciclosporin 5.Patents who treated with potassium-conserving diuretic 6.Pregnancy 7.Patients who hope of pregnancy 8.Severe infection 9.Patients who judge exclusion criteria by doctor

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The rate of patients who had normal ALT at 2 weeks from initial tacrolimus treatment The duration which had normal ALT at 2 weeks from initial tacrolimus treatment The rate of patients who had normal IgG at 2 weeks from initial tacrolimus treatment The duration which had normal IgG at 2 weeks from initial tacrolimus treatment The rate of patients who had normal ALT at 2 years from initial tacrolimus treatment The rate of patients who had normal IgG at 2 years from initial tacrolimus treatment Safety
Secondary Outcome Measures
NameTimeMethod
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