Contributing Factors to Anterior Resection Syndrome and Its Impact on Quality of Life: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 179
- 试验地点
- 1
- 主要终点
- LARS incidence
研究概览
简要总结
This study adds to the understanding of the contributing factors leading to LARS, the long term effects of this syndrome post-operatively and its impact on quality of life.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult patients >18 years, under the care of all surgical firms at Mater Dei Hospital, who had undergone anterior resection for rectal cancer between January 2014 and December 2016
排除标准
- •colorectal cancer (>15cm) from anal verge
- •permanent stoma
- •known disseminated or recurrent disease,
- •patient without restitution of bowel continuity after 1 year
结局指标
主要结局
LARS incidence
时间窗: 1 year
Incidence of LARS in patients who had anterior resection
Life
时间窗: 1 year
The association between LARS and quality of life was assessed.
Risk factors
时间窗: 1 year
Variable factors which might have contributed to LARS were the following: * Age * Gender * Diabetes mellitus * Pathological stage * MRI stage * Distance from anal verge * Surgical technique * Preoperative radiotherapy * Preoperative chemotherapy * Postoperative radio/chemotherapy * Type of anastomosis * Presence of stoma * Interval from stoma reversal * Duration of follow-up
次要结局
未报告次要终点
研究者
Svetlana Doris Brincat
Surgical trainee
University of Malta