Continuously Helm CPAP Versus Intermittent Mask CPAP After Major Abdominal Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 102
- 试验地点
- 2
- 主要终点
- PaO2/FiO2
研究概览
简要总结
Postoperative pulmonal complications (Abbreviation - PPC) after major abdominal surgery remains a significant clinical problem delaying rehabilitation after surgery. CPAP is one approach to minimize the frequency and severeness of PPC.
In the investigators' organization intermittent mask CPAP every 2 hour, 15min, is used routineously after major abdominal surgery.
Recently new devices has been designed, which give the opportunity tip deliver continuously CPAP with out interruptions because of presumed better comfort. Therefore better patient compliance.
No studies to date have investigated the possible benefit of using continuously helm CPAP versus the traditional intermittent mask CPAP after major abdominal surgery.
The investigators' study will investigate if there are any benefits with continuously Helm CPAP Versus intermittent Mask CPAP After Major Abdominal Surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective major abdominal surgery
排除标准
- •Severe lung disease. Airway deformity. Need for CPAP at home. Ongoing oxygen therapy. Cannot give informed consent.
结局指标
主要结局
PaO2/FiO2
时间窗: 24 hours
Measured 6,12 and 18 hours after surgery
次要结局
- V/Q mismatch(24 hours)
- Postoperative complications(30 days)
- Length of stay(30 days)
- Admittance to the intensive care unit(30 days)
- Mortality(30 days)
研究者
Klaus Vennick Marcussen
MD
Rigshospitalet, Denmark