To find out the benefit of alternate day versus daily oral iron therapy in iron deficient children

Not yet recruiting

Conditions: Iron deficiency anemia, unspecified,

Registration Number: CTRI/2023/08/056597

Lead Sponsor: DR PRANATI GROVER

Brief Summary: Iron deficiency anemia is the leading cause of nutritional anemia in India. It can cause both hematological as well as non hematological consequences such as stunted growth and impaired cognitive functions.Large amount of unabsorbed iron can cause gastric inflammation and decrease the compliance. Alternate day Iron therapy is more efficient than daily Iron therapy in improving the hemoglobin levels and this can be attributed to the increased hepcidin levels after daily Iron dose. Hepcidin is a negative regulator of iron absorption and increased levels will lead to decrease iron absorption.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

Patients between 6 months to 10 years of age diagnosed with iron deficiency anemia.

Exclusion Criteria

Patients who have received blood transfusion in past 3 months, oral or injectable iron supplements, patients with hemoglobinopathies, premature infants born before 32 weeks of gestation, patient with active infection.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the efficacy of alternate versus twice daily oral iron therapy in children with iron deficiency anemia	Over a span of one year

Secondary Outcome Measures

Name	Time	Method
1. Effect of alternate versus twice daily oral iron therapy on serum hepcidin levels	2. To compare the GI side effects in both the groups that may affect the compliance.

Trial Locations

Locations (1): KLEs Dr. PRABHAKAR KORE HOSPITAL BELAGAVI
🇮🇳
Belgaum, KARNATAKA, India
KLEs Dr. PRABHAKAR KORE HOSPITAL BELAGAVI
🇮🇳Belgaum, KARNATAKA, India
Dr PRANATI GROVER
Principal investigator
8106161797
pranati.grover@gmail.com