CTRI/2023/08/056597尚未招募不适用
Efficacy of alternate day versus daily oral iron therapy in children with iron deficiency anemia- A RANDOMIZED CONTROL TRIAL
DR PRANATI GROVER1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年8月30日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To assess the efficacy of alternate versus twice daily oral iron therapy in children with iron deficiency anemia
研究概览
简要总结
Iron deficiency anemia is the leading cause of nutritional anemia in India. It can cause both hematological as well as non hematological consequences such as stunted growth and impaired cognitive functions.Large amount of unabsorbed iron can cause gastric inflammation and decrease the compliance. Alternate day Iron therapy is more efficient than daily Iron therapy in improving the hemoglobin levels and this can be attributed to the increased hepcidin levels after daily Iron dose. Hepcidin is a negative regulator of iron absorption and increased levels will lead to decrease iron absorption.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 6.00 Month(s) 至 10.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients between 6 months to 10 years of age diagnosed with iron deficiency anemia.
排除标准
- •Patients who have received blood transfusion in past 3 months, oral or injectable iron supplements, patients with hemoglobinopathies, premature infants born before 32 weeks of gestation, patient with active infection.
结局指标
主要结局
To assess the efficacy of alternate versus twice daily oral iron therapy in children with iron deficiency anemia
时间窗: Over a span of one year
次要结局
- 1. Effect of alternate versus twice daily oral iron therapy on serum hepcidin levels(2. To compare the GI side effects in both the groups that may affect the compliance.)
研究者
研究点 (1)
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