Digital Capillary Refill for Monitoring of Sepsis

Oregon Health and Science University1 site in 1 country26 target enrollmentAugust 12, 2020

ConditionsSepsis

Overview

Observational study for monitoring of capillary refill time in sepsis

This is an observational studying assessing changes in capillary refill time over the course of sepsis treatment.

Registry

clinicaltrials.gov

Start Date

August 12, 2020

End Date

November 1, 2023

Last Updated

8 months ago

Study Type

Observational

Sex

All

Sponsor

Responsible Party

Principal Investigator

Dr. David Sheridan

Assistant Professor of Emergency Medicine

Oregon Health and Science University

•Clinical evidence of a known or suspected infection and orders written for administration of IV antibiotics
•Hypotension as defined by the need for any vasopressor (and 1 liter of fluid already administered) OR respiratory failure defined by assisted ventilation (includes mechanical ventilation and BIPAP), CPAP, or greater than or equal to 6 liters/minute of supplemental oxygen

•No consent/inability to obtain consent from the participant or a legally authorized representative
•Diagnosis of cirrhosis by medical chart review
•Liver transplant recipient
•AST or ALT greater than five times upper limit of normal
•Diagnosis of ongoing chronic alcohol use disorder/abuse by chart review; if medical record unclear, use Appendix F
•Clinical diagnosis of diabetic ketoacidosis or other condition such as profound hypoglycemia that requires hourly blood glucose monitoring
•Hypersensitivity to Acetaminophen or Vitamin C
•Patient, surrogate or physician not committed to full support (Exception: a patient will not be excluded if he/she would receive all supportive care except for attempts at resuscitation from cardiac arrest)
•Home assisted ventilation (via tracheotomy or noninvasive) except for CPAP/BIPAP used only for sleep-disordered breathing
•Current active kidney stone