Observation study to evaluate treatment responses to inhaled corticosteroids and long-term clinical courses in patients with cough variant asthma or eosinophilic bronchitis

Asan Medical Center0 个研究点目标入组 120 人开始时间: 待定最近更新: 2021年1月6日

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•?Adults over 19 years old
•?Those presenting with cough that has lasted more than 8 weeks
•?Baseline FeNO of 30 ppb or more, suggesting the diagnosis of cough variant asthma and eosinophilic bronchitis
•?Those being about to treat with ICS depending on the diagnosis of cough asthma or eosinophilic bronchitis
•?Those without symptoms and signs, such as wheezing, dyspnea, heartburn, acid reflux, fever, and purulent sputum, suggesting cough related diseases other than cough variant asthma and eosinophilic bronchitis that require treatment
•?Non-smoker for more than 1 month and those not taking ACE inhibitors
•?FEV1>80%, FEV1/FVC>70% or more in lung function test within last 1 month
•?Those who are considered not to be related to chronic cough by the researcher's decision, even if there are abnormal findings on chest radiography within the last 1 month
•?No medication history of steroids and leukotriene receptor antagonists within the last 2 weeks
•?No medication history of opiate antitussive drugs such as codeine within the last 1 week

•?Those who cannot use ICS properly
•?Those who have a severe cough and require prescription of opioid antitussive drugs such as codeine
•?Those who have any physical factors that may affect cough
•?Those who are likely to become pregnant within 1 month, plan to become pregnant, or are pregnant

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