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临床试验/ISRCTN28785798
ISRCTN28785798已完成未知

A prospective, randomized, unicentric study investigating the non-inferiority of combined oral diuretics furosemide and hydrochlorothiazide/amiloride to intravenous furosemide in patients with nephrotic edema and diuretic resistance

Institutul Clinic Fundeni0 个研究点目标入组 22 人开始时间: 2020年12月29日最近更新:

试验速览

阶段
未知
状态
已完成
入组人数
22

研究概览

简要总结

2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37959360/ (added 07/12/2023)

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Age >18 years old
  • 2. Nephrotic syndrome in patients without diabetes mellitus
  • 3. Diuretic resistance
  • 4. eGFR >30 ml/min/1.73 m²

排除标准

  • 1. Age <18 years old
  • 2. Nephrotic syndrome in patients with type 1 or type 2 diabetes
  • 3. eGFR <30 ml/min/1.73 m²
  • 4. Hypokalemia and hyperkalemia
  • 5. Severe hyponatremia
  • 6. Alcalosis
  • 7. Severe pulmonary congestion
  • 8. Active infection
  • 9. NSAIDs use within the last month
  • 10. Pregnancy
  • 11. Kidney transplant
  • 12. Known allergy to furosemide, hydrochlorothiazide or amiloride
  • 13. Patients with a defibrillator/pacemaker/metal prosthesis

研究者

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