ISRCTN28785798已完成未知
A prospective, randomized, unicentric study investigating the non-inferiority of combined oral diuretics furosemide and hydrochlorothiazide/amiloride to intravenous furosemide in patients with nephrotic edema and diuretic resistance
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 22
研究概览
简要总结
2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37959360/ (added 07/12/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age >18 years old
- •2. Nephrotic syndrome in patients without diabetes mellitus
- •3. Diuretic resistance
- •4. eGFR >30 ml/min/1.73 m²
排除标准
- •1. Age <18 years old
- •2. Nephrotic syndrome in patients with type 1 or type 2 diabetes
- •3. eGFR <30 ml/min/1.73 m²
- •4. Hypokalemia and hyperkalemia
- •5. Severe hyponatremia
- •6. Alcalosis
- •7. Severe pulmonary congestion
- •8. Active infection
- •9. NSAIDs use within the last month
- •10. Pregnancy
- •11. Kidney transplant
- •12. Known allergy to furosemide, hydrochlorothiazide or amiloride
- •13. Patients with a defibrillator/pacemaker/metal prosthesis
研究者
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