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临床试验/NCT07468825
NCT07468825尚未招募不适用

Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder

Assistance Publique - Hôpitaux de Paris1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年4月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
试验地点
1
主要终点
Uncertainty Cost Index During Behavioral Adaptation Task

研究概览

简要总结

Alcohol Use Disorder (AUD) is a chronic condition that affects behavior, decision-making, and the ability to adapt to changing situations. While many studies have examined AUD from medical and social perspectives, less is known about how individual psychological traits influence the way people with AUD respond to uncertainty and adapt their behavior.

This study aims to better understand how personal characteristics such as anxiety, self-esteem, sensitivity to reward and punishment, perfectionism, and cognitive abilities may influence adaptation processes in individuals with AUD.

Participants receiving usual care at Paul Brousse Hospital will be invited to take part in a single experimental session lasting about 45 minutes. During this session, they will complete:

  • A computerized learning task in which they respond to visual stimuli and receive feedback on their performance
  • Standardized questionnaires assessing psychological traits and cognitive functioning

The learning task is designed to evaluate how participants adjust their behavior when the rules of the task change unexpectedly. Researchers will measure how performance changes in response to uncertainty and examine how these changes relate to individual psychological characteristics.

This research does not modify participants' medical care and involves no medication or invasive procedures.

By improving understanding of the cognitive and behavioral mechanisms involved in Alcohol Use Disorder, the study may help advance scientific knowledge about how individuals adapt to uncertainty and inform future research in addiction and mental health.

详细描述

Alcohol Use Disorder (AUD) is associated with difficulties in decision-making and behavioral adaptation, particularly in situations involving uncertainty. Individual psychological traits may influence how people with AUD adjust their behavior when facing changing environments, but this relationship remains insufficiently understood.

This monocentric, non-interventional study aims to explore how individual traits influence adaptive processes in adults diagnosed with Alcohol Use Disorder.

Participants receiving usual care at Paul Brousse Hospital will attend a single experimental session lasting approximately 45 minutes. During this session, they will perform a computerized learning task designed to evaluate behavioral adaptation when task rules change unexpectedly. They will also complete standardized questionnaires assessing personality traits and cognitive functioning.

Behavioral performance during the task will be analyzed to measure adaptation to uncertainty and examined in relation to individual psychological characteristics.

The study does not involve medication, medical devices, or any modification of clinical care.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 18 years or older
  • Patients receiving care for Alcohol Use Disorder at the Psychiatry and Addiction Unit of Paul Brousse Hospital
  • No objection to participation in the study

排除标准

  • Diagnosed neurological disorder
  • Patient covered by State Medical Assistance (AME)
  • Individuals under legal protection measures (guardianship, curatorship, or legal safeguard)
  • Individuals deprived of liberty by judicial or administrative decision
  • Pregnant or breastfeeding women
  • Psychiatric disorders that could compromise proper study participation (excluding Alcohol Use Disorder)

结局指标

主要结局

Uncertainty Cost Index During Behavioral Adaptation Task

时间窗: At the end of the learning phase and at the beginning of the uncertainty phase during the single study session (approximately 45 minutes)

Uncertainty cost index. Exploration-exploitation behaviors are inferred from the percentage of correct responses obtained during the CHEAT phase of the computerized task. For each participant, the difference in accuracy rate between the end of the learning phase and the beginning of the CHEAT phase is calculated. This difference (Δ) defines the uncertainty cost index and reflects exploratory behavioral responses to the introduction of misleading feedback.

次要结局

  • Correlation Between Uncertainty Cost Index and Psychometric Trait Scores(During the single study session (approximately 45 minutes))

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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