High Fresh Gas Flow After Intubation - A Randomized Clinical Trial

Region Västmanland1 site in 1 country24 target enrollmentSeptember 2014

ConditionsAtelectasis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Atelectasis
Sponsor: Region Västmanland
Enrollment: 24
Locations: 1
Primary Endpoint: Atelectasis
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Atelectasis is common during and after general anesthesia. Atelectasis develops early if preoxygenation with 100% oxygen is used and continuously used during induction until endotracheal intubation. The investigators hypothesize that a rapid anti-preoxygenation maneuver immediately after confirming a successful intubation, reduces the area of atelectasis as investigated by computed tomography compared to a standard procedure.

Registry

clinicaltrials.gov

Start Date

September 2014

End Date

May 2015

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Region Västmanland

Responsible Party

Principal Investigator

Erland Ostberg

M.D.

Region Västmanland

Eligibility Criteria

Inclusion Criteria

•Healthy patients, American Society of Anesthesiology (ASA) I-II
•Patients scheduled for orthopaedic day case surgery in general anaesthesia

Exclusion Criteria

•ASA class III or higher
•Body Mass Index (BMI) 30 or higher
•Arterial oxygen saturation (SpO2) \<94% breathing air
•Chronic Obstructive Pulmonary Disease (COPD)
•Ischemic heart disease
•Haemoglobin \<100g/L
•Known or anticipated difficult airway and/or intubation
•Active smokers and ex-smokers with a history of more than 6 pack years
•Need for interscalene or supraclavicular regional anaesthesia with risk of phrenic nerve paralysis

Outcomes

Primary Outcomes

Atelectasis

Time Frame: Within 1-2 hours, just before emergence from anesthesia

The area of atelectasis in the lungs is assessed by computed tomography (CT) 10 mm above the dome of the right diaphragm and expressed in cm2 and as % of the total lung area in the particular scan.