The effect of synbiotic on burn infections
Phase 3
- Conditions
- patient with major burn 25-50 percent.
- Registration Number
- IRCT20190423043354N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 170
Inclusion Criteria
Burn percent 25-50
No use of any prebiotic, probiotic or synbiotic in last 2 months before the study starts
Patients with stable condition
Exclusion Criteria
Use of dopamine and epinephrine
Pregnancy and breast feeding
Allergy to melatonin
Bowel obstruction - ileus - gastroparesy or any condition that affect enteral absorption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Positive sputum culture. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Sputum culture.;Positive blood culture. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Blood culture.;Positive urinary culture. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Urinary culture.;Positive catheter infection. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Clinician examination - catheter culture.
- Secondary Outcome Measures
Name Time Method