Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diabetes Mellitus, Type 2
- Sponsor
- Baqiyatallah Medical Sciences University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Life Quality
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms. The variables of contrast sensitivity, macula thickness under fovea , BCVA, the width of thyroid under fovea , RNFL thickness in the four areas around the disc, and the quality of life questionnaire of all patients were recorded at the beginning of the study.Retinal and choroid under fovea thickness and RNFL thickness were assessed in four areas, one week and one month after the end of treatment, and all the variables mentioned earlier were evaluated three months after PRP surgery.
This study is single group that the outcomes are compared before and after the intervention
Investigators
Mohammad Sadegh Bagheri Baghdasht
Principal Investigator
Baqiyatallah Medical Sciences University
Eligibility Criteria
Inclusion Criteria
- •Diabetes Mellitus, Type 2 with PDR
- •Having conscious satisfaction
Exclusion Criteria
- •Patients with a history of other eye diseases
- •Patients with a history of previous laser treatment
- •Patients with a history of injection of Anti-VGEF
- •Patients with Vitreous hemorrhage
- •Patients with Macula edema
- •Patients with myopia more than -3 diopters or hyperopiamore than +3 diopters
Outcomes
Primary Outcomes
Life Quality
Time Frame: up to 3 months
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease Which is measured by a quality of life questionnaire
RNFL
Time Frame: up to 30 days
retinal nerve fiber layer which measured by PP-OCT (optical coherence tomography)
Retinal thickness in the central part of Fovea
Time Frame: up to 30 days
Measured by SD-OCT
Choroid thickness in the central part of Fovea
Time Frame: up to 30 days
Measured by EDI-OCT
BCVA
Time Frame: up to 3 months
best corrected visual acuity which measured by SD-OCT
Contrast sensitivity
Time Frame: up to 3 months
Contrast sensitivity which measured by Melbourne edge test
Angiography with fluorescein
Time Frame: up to 3 months
By injecting fluorescein into the vein and then taking an X-ray to diagnose PDR
Physical examination of PDR
Time Frame: up to 3 months
An eye exam performed by an ophthalmologist will determine if there is retinopathy