A Clinical Study to Evaluate the Anti-pigmentation and brightening activity of Plum Vitamin C Serum

Pureplay Skin Science Pvt Ltd1 个研究点分布在 1 个国家目标入组 32 人开始时间: 2025年2月25日

试验速览

An open label one arm study to check Saftey and tolerability for anti-pigmentation and brightness

Assessment Points:

Skin Gloss by Glossymeter (T0, T1 hour, Day 5, and 14)

Skin Pigmentation by Mexameter Face(Melanin Index) (Day 0, 5, 14)

Skin Hydration by Corneometer (T0, T1hour)

Dark Spots by Visioface (Day 0, 5, 14)

Skin discoloration by Chromameter as L value in L*a*b space (Day 0, 5, 14)

Skin Barrier by TEWAMETER (Day 0, 5, 14)

Test Duration-14 volunteers, Volunteers-32

•Gender: Male or Female with age 18-45 2) Subjects with pigmented skin, with a self-declared pigmented due to UV exposure.
•Subjects willing to give written informed consent 4) Women of child bearing potential must have a negative urine pregnancy test prior to study entry.
•Are free of any systemic or dermatologic disorder, which, in the opinion of the investigator, will interfere with the study results or increase the risk of adverse events.
•Are willing to avoid prolonged exposure of the treatment area to ultraviolet radiation (natural or artificial) for the duration of the study.

•1.Subjects who are pregnant, breast-feeding, or planning to become pregnant during the study.
•2.Have any evidence of systemic cancer, squamous cell carcinoma, basal cell carcinoma, in the last 5 years, or any other confounding skin condition.
•3.Have open sores or open lesions in the treatment area(s).
•4.Have any condition that, in the opinion of the investigator, would confound the safety and/or efficacy assessments of the product.
•5.Have participated in any interventional clinical trial in the previous 30 days.
•6.Have a known sensitivity to any of the constituents of the test product including sensitivities to (mention some of active ingredient’s name) 7.Have used, are using, or are planning to use immunosuppressive or immunomodulatory medication (i.e., biologics), including corticosteroids.
•8.Have a history of alcohol or illegal drug/substance abuse, or suspected alcohol or illegal drug/substance abuse in the past 2 years.