Sugammadex vs Neostigmine for Reversal of Neuromuscular Blockade: Recovery Profile and Postoperative Complication
Trial Snapshot
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
Study Overview
Brief Summary
This study compares Sugammadex and Neostigmine for the reversal of neuromuscular blockade in patients undergoing general anesthesia. The aim is to evaluate which drug provides faster and more reliable recovery of muscle function and to assess the incidence of postoperative complications. The primary outcome is the time taken to achieve adequate neuromuscular recovery after administration of the reversal agent. Secondary outcomes include extubation time, return of clinical recovery signs, and postoperative events such as nausea, vomiting, desaturation, bradycardia, diplopia, and urinary retention during the first twenty four hours. This study will help determine whether Sugammadex offers significant clinical advantages over neostigmine in routine anesthesia practice.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •1.ASA I and II 2.Elective surgeries with vecuronium 3.Informed consent.
Exclusion Criteria
- •1.Neuromuscular disorders 2.Hepatic/renal dysfunction 3.Known allergy to study drugs 4.Pregnancy/lactation.
Investigators
Dr S Shanu
Vinayaka Missions Kirupananda Variyar Medical College and Hospitals
