Application of Electrically Driven Atomized Surface Anesthesia in ATI in Patients With Predictably Difficult Airway.
- Conditions
- Anesthesia, Endotracheal
- Interventions
- Other: atomizer
- Registration Number
- NCT06420947
- Lead Sponsor
- Henan Provincial People's Hospital
- Brief Summary
This is a parallel and randomized-controlled clinical study aimed to identify the optimized size of atomized particles of 2% lidocaine that can provide the best topical anesthesia during ATI. To determine the effect of nebulization with different sizes of atomized particles of 2% lidocaine on cough, reaction, and comfort during ATI in patients with predicted difficult airway.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 230
Patients with distinctly difficult airways：(1) Patients with medical history indicating difficult airways.(2) Patients suffering from severe burn scars.(3) Patients suffering from severe obstructive sleep apnea syndrome.(4)Patients suffering from severe congenital dysplasia.
Patients with suspected difficult airway:
Patients with risk factors underwent a medical history for evaluation:(1)Patients with ankylosing spondylitis.(2) Patients with rheumatoid arthritis.(3)Patients with degenerative osteoarthritis.(4)Patients with epiglottitis. (5)Patients with acromegaly.(6)Patients with morbid obesity.(7)Patients with subglottic stenosis. (8) Patients with enlarged thyroid or tonsils.(9)Patients with mediastinal mass.(10)Patients with throat tumors.
Patients with risk factors underwent a physical examination for evaluation:(1)Patients with BMI > 26 kg/m2. (2)Patients with Mallampati class 3 or 4. (3)Patients with thyromental distance<60 mm (corresponding to an average distance of 3 finger breadths).(4)Patients with limited mouth opening with interincisor distance<30 mm.(5)edentulous patients.(6)When the patient closed his mouth in a natural state, the upper incisor was situated in front of the lower incisor.(7)When the mandible is extended forward, the lower incisors of the patient can not protrude beyond the upper incisors.(8)The patient's jaw exhibits stiffness, with minimal elasticity or presence of a tumor.(9)The patients have a short neck with a thick circumference.(10)The patients are unable to touch their chest wall with their jaw, or extend their neck.(11)The patients's palate shape is either characterized by a high arch or is extremely narrow.
(1) refusal to participate in the study; (2) airway bleeding; and (3) known allergies to local anesthetics.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group A atomizer Participants in the A group received 2% lidocaine by A model atomizer. Group B atomizer Participants in the B group received 2% lidocaine by B model atomizer. Group C atomizer Participants in the C group received 2% lidocaine by C model atomizer. Group D atomizer Participants in the D group received 2% lidocaine by D model atomizer.
- Primary Outcome Measures
Name Time Method cough score during intubation Investigators will record cough score during intubation.
- Secondary Outcome Measures
Name Time Method reaction and discomfort scores during intubation. Investigators will record reaction and discomfort scores during intubation.
intraoperative hemodynamic parameters endotracheal tube insertion, inflation of the tracheal tube cuff and 1 minute after endotracheal tube insertion endotracheal tube insertion inflation of the tracheal tube cuff systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR)
Trial Locations
- Locations (1)
Henan Provincial People's Hospital
🇨🇳Zhengzhou, Henan, China