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Comparison the Effect of Cinnarizine and Amitriptyline in Pediatric Migraine

Phase 3
Recruiting
Conditions
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Migraine
Registration Number
IRCT20191112045413N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
70
Inclusion Criteria

Having experienced one or more migraine attacks per month or severe dysfunction in daily and school activities

Exclusion Criteria

Use of prophylactic migraine therapy in at least one previous month
Focal Neurologic Deficit
Known concomitant serious diseases (hepatic, renal, etc)

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Percent of patients who the severity of their headache episodes decreased to less than 50% of baseline. Timepoint: One month before to 3 months after initiation of treatment. Method of measurement: Visual Analogue Scale and Visual Pain Scale.;Percent of patients who the frequency of their headache episodes decreased to less than 50% of baseline. Timepoint: One month before to 3 months after initiation of treatment. Method of measurement: By charting all the headache episodes by detail in the special checklist.;Percent of patients who the duration of their headache episodes decreased to less than 50% of baseline. Timepoint: One month before to 3 months after initiation of treatment. Method of measurement: By charting all the headache episodes by detail in the special checklist.
Secondary Outcome Measures
NameTimeMethod
Quality of life scoring. Timepoint: One month before to 3 months after initiation of treatment. Method of measurement: PedMIDAS questionnaire.
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