Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis: a prospective randomised trial

Academic Medical Centre (AMC) (Netherlands)0 个研究点目标入组 39 人开始时间: 2005年12月20日最近更新: 2015年1月13日

试验速览

暂无简介。

•1. A diagnosis of CP, based on clinical symptoms in combination with morphological changes established by imaging studies (calcifications or ductal changes) and/or pancreatic functional insufficiency
•2. A dominant obstruction of the pancreatic duct, demonstrated by presence of a stenosis and/or intraductal stones on magnetic resonance cholangiopancreatography (MRCP) and abdominal computed tomography (CT) scan, located left from the spine, with pre-stenotic ductal dilatation of at least 5 mm
•3. Severe recurrent pancreatic pain with insufficient relieve by non-narcotic analgesics or requiring opiates

•1. Age below 18 or over 80 years
•2. Pancreatic head enlargement greater than 4 cm
•3. Contra-indication for surgery; American Society of Anaesthesiologists (ASA) class 4, severe portal hypertension
•4. Contra-indications for endoscopy: gastrectomy with Billroth II reconstruction, other pancreatitis related complications (bile duct stricture, pseudocyst) requiring surgery
•5. Previous pancreatic surgery
•6. Suspected pancreatic malignancy
•7. Limited life expectancy (less than 2 years)
•8. Pregnancy

发起方

Academic Medical Centre (AMC) (Netherlands)