Effect of zinc supplementation on tuberculosis therapy

Phase 1

• Conditions: Pulmonary tuberculosis.; infections due to Mycobacterium tuberculosis and Mycobacterium bovis; A15-A19

• Registration Number: IRCT201112178429N1
• Lead Sponsor: Institute Pasteur of Iran

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Inclusion criteria includes having tuberculosis and filling the informed consent

Exclusion criteria includes getting diseases such as cancer, stroke, immiunosupprision diseases and not taking mineral supplement or placebo

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Stop fever. Timepoint: At the baseline ,2 month and 6 month later. Method of measurement: Physical exam.;Radiological signs. Timepoint: At the baseline ,2 month and 6 month later. Method of measurement: Chest radiology.;Smear negative. Timepoint: At the baseline ,2 month and 6 month later. Method of measurement: Smear.;Stop coughing. Timepoint: At the baseline ,2 month and 6 month later. Method of measurement: Physical exam.

Secondary Outcome Measures

Name	Time	Method
Serum Zinc. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: Atomic Absorption.;Serum Copper. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: Atomic Absorption.;Serum Fe. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: RA 1000.;Serum ALK. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: RA 1000.;Serum Albumin. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: RA 1000.;Body Mass Index. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: weight(kg)/height2 (m2).;Serum SGPT. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: RA 1000.;Serum SGOT. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: RA 1000.;Serum total protein. Timepoint: At baseline ,2 month and 6 month later. Method of measurement: RA 1000.