ACTRN12608000053325招募中3 期
A multi-centre, randomised controlled trial of the effect of early goal-directed therapy, compared to standard care, on 90-day mortality in patients presenting to the Emergency Department with severe sepsis in Australasia
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 1,600
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 /A（—）
- 性别
- All
入选标准
- •1. Suspected or confirmed infection
- •2. 2 or more systemic inflammatory response syndrome (SIRS) criteria
- •3. Evidence of either refractory hypertension or hypoperfusion
排除标准
- •Contra-indication to superior vena cava central venous catheter insertion; contra-indication to blood products; inability to commence delivery of EGDT protocol within 1 hour of randomisation or complete 6 hours of EGDT; haemodynamic instability due to active bleeding; pregnancy; transfer from another ED or acute health care facility; the patient has an underlying disease process with a life expectancy of < 90 days; death is deemed imminent and inevitable; a limitation of therapy order has been documented
研究者
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