High-sensitivity C-reactive Protein and United Kingdom Prospective Diabetes Study (UKPDS) Risk Score in Type 2 Diabetes

Completed

• Conditions: Atherosclerosis; Type 2 Diabetes

• Registration Number: NCT01099865
• Lead Sponsor: Korea University

Brief Summary

The UKPDS risk score is recommended to assess global risk for future coronary heart disease (CHD) events in primary prevention. Recently, high-sensitivity C-reactive protein (hsCRP) has emerged as a strong independent risk factor for CHD. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising imaging technique for the evaluation of vascular inflammation that reflects vulnerable atherosclerotic plaque.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-12
• Status Verified: 2010-04
• Primary Completion: 2010-04
• Study Completion: 2010-04
• Study First Submitted: 2010-04-07
• Study First Submitted QC: 2010-04-07
• Last Update Submitted: 2010-04-07
• Study First Posted: 2010-04-08
• Last Update Posted: 2010-04-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• Type 2 diabetes

Exclusion Criteria

• Myocardial infarction, unstable angina, stroke, peripheral artery disease, or cardiovascular revascularization
• Resting blood pressure ≥160/100 mmHg
• Malignancy, or severe renal or hepatic disease
• Participants were free of any lipid-lowering therapies and postmenopausal hormone replacement therapy at least the 6 month period prior to enrollment
• History of inflammatory condition or those taking medications that might affect inflammatory status within 6 months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Korea University Guro Hospital Dept. of Endocrinology; 🇰🇷 Seoul, Korea, Republic of