Frailty Score Assessment for Elderly Patients Undergoing Cardiac Resynchronization Therapy
- Conditions
- Heart Failure
- Interventions
- Other: Frailty
- Registration Number
- NCT02369419
- Lead Sponsor
- Centre Hospitalier Universitaire, Amiens
- Brief Summary
Background: The cardiac resynchronization therapy (CRT) has been shown to improve symptoms and outcome of patients with congestive heart failure (HF), and depressed left ventricular ejection fraction (LVEF \< 35 %). The rate of non-responders to CRT is estimated at 30 %. Yet, the impact of frailty on the response to CRT has not been studied, until now.
Purpose : To assess the impact of frailty in the elderly, on the response to CRT.
- Detailed Description
Methods : Frailty is evaluated before implant ,and defined as \<14/17 points using the ONCODAGE score, in 150 patients of \> 70 years age, selected for CRT according to the ESC 2013 guidelines. The response to CRT, estimated at 9 months, is defined as an improvement of at least 5 % of the LVEF and the absence of HF hospitalization or cardiovascular death.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 150
- Patients of > 70 years age,
- Selected for CRT according to the ESC 2013 guidelines
- patients included in other clinical trial which can interfere with the results of this one
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description CRT Frailty Patients over 70 years age, selected for CRT according to the ESC 2013 guidelines.
- Primary Outcome Measures
Name Time Method non response on CRT 9 months
- Secondary Outcome Measures
Name Time Method seric albumin 9 months To assess the impact of seric albumin on the response to CRT
seric gammaglutamyltranferase 9 months To assess the impact of seric gammaglutamyltranferase on the response to CRT
mortality 9 months
Trial Locations
- Locations (1)
CHU; Service de Cardiologie, Rythmologie et Stimulation cardiaque
🇫🇷Amiens, France