Early Renal Replacement Therapy and the Outcome of Acute Kidney Injury
Not Applicable
Completed
- Conditions
- Acute Renal Failure
- Interventions
- Procedure: continuous renal replacement therapy
- Registration Number
- NCT01819038
- Lead Sponsor
- Chulalongkorn University
- Brief Summary
This research project is a prospective study to compare mortality between early renal replacement therapy (RRT) and late renal replacement therapy by using plasma neutrophil gelatinase associated lipocalin (pNGAL) as a tool in decision- making.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- The patient must have given his/her informed and signed consent
- patients with acute kidney injury in the intensive care ward.
Exclusion Criteria
- The patient refuses to sign the consent
- The patient is pregnant, parturient, or breastfeeding
- End stage renal disease
- Chronic renal failure
- previous kidney transplant
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description High NGAL and early RRT continuous renal replacement therapy NGAL level \> 400 ng/ml and start continuous renal replacement therapy early High NGAL and late RRT continuous renal replacement therapy NGAL \> 400 ng/ml and start continuous renal replacement therapy late Low NGAL continuous renal replacement therapy NGAL \< 400 ng/ml and starting continuous renal replacement therapy follow with absolute indication
- Primary Outcome Measures
Name Time Method mortality rate 28 day
- Secondary Outcome Measures
Name Time Method ventilator free-days 28 days
Trial Locations
- Locations (1)
King Chulalongkorn Memorial Hospital
🇹🇭Bangkok, Thailand