NCT01819038已完成不适用
Early Renal Replacement Therapy and the Outcome of Acute Kidney Injury
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- mortality rate
研究概览
简要总结
This research project is a prospective study to compare mortality between early renal replacement therapy (RRT) and late renal replacement therapy by using plasma neutrophil gelatinase associated lipocalin (pNGAL) as a tool in decision- making.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient must have given his/her informed and signed consent
- •patients with acute kidney injury in the intensive care ward.
排除标准
- •The patient refuses to sign the consent
- •The patient is pregnant, parturient, or breastfeeding
- •End stage renal disease
- •Chronic renal failure
- •previous kidney transplant
研究组 & 干预措施
High NGAL and early RRT
Experimental
NGAL level > 400 ng/ml and start continuous renal replacement therapy early
干预措施: continuous renal replacement therapy (Procedure)
High NGAL and late RRT
Experimental
NGAL > 400 ng/ml and start continuous renal replacement therapy late
干预措施: continuous renal replacement therapy (Procedure)
Low NGAL
Active Comparator
NGAL < 400 ng/ml and starting continuous renal replacement therapy follow with absolute indication
干预措施: continuous renal replacement therapy (Procedure)
结局指标
主要结局
mortality rate
时间窗: 28 day
次要结局
- ventilator free-days(28 days)
研究者
Nattachai Srisawat ,M.D.
Principle Investigator
Chulalongkorn University
研究点 (1)
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