Allelic Linkage in Substance Abuse

National Institute on Drug Abuse (NIDA)1 site in 1 country8,000 target enrollmentAugust 1992

ConditionsSubstance Abuse

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Substance Abuse
Sponsor: National Institute on Drug Abuse (NIDA)
Enrollment: 8000
Locations: 1
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This investigation seeks to better define the genetic basis for vulnerability to substance abuse.

Detailed Description

Dopamine (DA), a neurotransmitter helping to mediate reward and reinforcement, has been putatively linked to the development of substance abuse, alcohol abuse, and alcoholism. Identification of specific vulnerability-association alleles for receptors, other molecules within the reward mediating system, and other genes that may predispose individuals to the development of such disorders is the goal of the study. This investigation will help elucidate the genetic underpinnings of substance abuse, potentially leading to the improved methods to diagnose those at risk and to help develop better therapeutic interventions.

Registry

clinicaltrials.gov

Start Date

August 1992

End Date

February 2006

Last Updated

9 years ago

Study Type

Observational

Sex

All