Clinical Utility and Outcome Prediction of Cardiovascular Computed Tomography (PREDICT-CT)
Overview
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 4,200
- Locations
- 1
- Primary Endpoint
- All-cause death.
Overview
Brief Summary
In this study the investigators retrospectively and prospectively collect information from enrolled subjects undergoing CCTA and evaluate the association of cardiac and non-cardiac imaging with laboratory markers and clinical data including outcome.
Detailed Description
In this study the investigators retrospectively and prospectively collect information from enrolled subjects through a period of a total of 10 years to evaluate multidimensional associations between phenotypic manifestations of cardiovascular disease via CCTA and cardiac and non-cardiac imaging, serum biomarkers, demographic and clinical information, clinical presentation (cross-sectional), therapy changes (time-varying) and their ability to predict mortality and MACE (major adverse cardiac event ) (longitudinal) in patients clinically indicated for CCTA.
The aim is to establish a comprehensive cross-sectional, time-varying and longitudinal data collection for individuals undergoing clinically-indicated CCTA to date in order to apply novel multiparametric approaches to determine cardiovascular significance to clinically-important patient-centered events. For data collection this registry will follow a standard CRF (case report form) structure, so to enable the merging of this data-set with other international registries, which might contribute in overcoming some gaps of knowledge from previous CCTA studies.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adult individual \>18 years
- •Undergoing clinically indicated CCTA
- •Signed informed consent or waiver
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
All-cause death.
Time Frame: 10 years
The primary endpoint is the time to first occurrence of death from all-causes.
Secondary Outcomes
- Other outcome(10 years)
- Major adverse cardiovascular events (MACE)(10 years)