Effects of Whole-Body Vibration Exercise on Serum IGF-1 in Fibromyalgia
- Conditions
- FibromyalgiaHormonal Responses to Exercise in Patients With Fibromyalgia.
- Registration Number
- NCT00650715
- Lead Sponsor
- Institut Nacional d'Educacio Fisica de Catalunya
- Brief Summary
The purpose of this study was to investigate the acute and chronic effect of whole-body vibration exercise on serum insulin-like growth factor-1 levels in women with fibromyalgia (FM). It was hypothesized that women with FM would exhibit an increase in IGF-1 following both acute and chronic WBV. Twenty-four women with FM were randomized into two groups: Vibration Group (VG) and Control Group (CG). The VG underwent a protocol with WBV exercise twice a week for a total of six weeks, whereas the CG performed the same protocol without vibratory stimulus. Both groups continued with their usual pharmacological treatment. Serum IGF-1 levels were determined using Enzyme-Linked Immunosorbent Assay (ELISA). To test the effect of chronic WBV, serum IGF-1 measurements were taken at baseline and at weeks 1,3, and 6 of intervention. To test the effect of acute WBV, within week 1, serum IGF-1 measurements were taken before and immediately following a session of WBV.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 24
- Patients diagnosed of fibromyalgia according to the American College of Rheumatology criteria for at least three years.
- Orthopedic limitation, or cardiovascular, pulmonary, or metabolic disease that would preclude exercise.
- Participation in any other study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Serum IGF-1 levels Baseline, Week 1, Week 3, Week 6
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Institut Nacional d'Educación Física de Catalunya
🇪🇸Barcelona, Spain
Institut Nacional d'Educación Física de Catalunya🇪🇸Barcelona, Spain