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Clinical Trials/NCT04855981
NCT04855981
Completed
N/A

Effect of Whole-body Vibration Versus Aerobic Exercise on the Inflammatory Status and Hormonal Parameters in Females With Premenstrual Syndrome

Cairo University1 site in 1 country105 target enrollmentApril 15, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Premenstrual Syndrome
Sponsor
Cairo University
Enrollment
105
Locations
1
Primary Endpoint
premenstrual symptoms
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this study is to investigate and compare the effect of whole-body vibration to aerobic exercise on inflammatory status in females with premenstrual syndrome.

Detailed Description

Premenstrual syndrome (PMS) is a complex disorder characterized by moderate to severe symptoms taking place during the luteal phase of the menstrual cycle. It has a negative impact on females' lives, which can affect their relationships, educational efficiency, social activities, and quality of life. Despite previous studies reported that physical exercise improves the symptoms of PMS, the effects of physical exercise on inflammatory status in females with PMS are not clear yet. sixty females allocated to three groups randomly to group (A) that will receive whole-body vibration+supplementation, group (B) that will receive aerobic exercises+supplementation, and group c that will receive supplementation only

Registry
clinicaltrials.gov
Start Date
April 15, 2021
End Date
May 30, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Al Shaymaa Shaaban Abd El Azeim

Principale investigator. al shaymaa shaaban abd el azeim

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Females suffering from PMS (as determined by PMS scale).
  • Their ages will range from 18 to 25 years.
  • Having regular menstrual cycle.

Exclusion Criteria

  • Taking any medications.
  • History of chronic disease.
  • Having any psychiatric or gynecological problems

Outcomes

Primary Outcomes

premenstrual symptoms

Time Frame: up to twelve weeks

The premenstrual syndrome questionnaire also measured the occurrence and severity of two menstrual pain symptoms, including cramp and backache experienced during the first 2 days of the women' last menstrual period. Premenstrual symptoms were scaled as: mild (1); moderate (2); and severe (3). Young women with PMS should experience a premenstrual symptoms score of at least 50% greater than the postmenstrual score

Secondary Outcomes

  • cortisol level(up to twelve weeks)
  • CRP level assessment(up to twelve weeks)
  • hormonal analysis(up to twelve weeks)

Study Sites (1)

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