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Clinical Trials/NCT05759065
NCT05759065
Recruiting
Not Applicable

A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care

Brigham and Women's Hospital1 site in 1 country350 target enrollmentApril 2, 2024
ConditionsInsomnia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Insomnia
Sponsor
Brigham and Women's Hospital
Enrollment
350
Locations
1
Primary Endpoint
Insomnia severity index, ISI
Status
Recruiting
Last Updated
8 months ago

Overview

Brief Summary

The overall objective of this study is to conduct a randomized effectiveness-implementation trial to test the non-inferiority of tele-Brief Behavioral Treatment for Insomnia vs. tele-Cognitive-Behavioral Therapy for Insomnia among socioeconomically disadvantaged adults with insomnia in the primary care setting.

Registry
clinicaltrials.gov
Start Date
April 2, 2024
End Date
June 1, 2027
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Suzanne M. Bertisch, MD, MPH

Associate Physician, Clinical Director of Behavioral Sleep Medicine

Brigham and Women's Hospital

Eligibility Criteria

Inclusion Criteria

  • Aged 18 years or older
  • Meet clinical diagnostic criteria for insomnia
  • Insomnia severity score \> 10
  • Eligible to receive care through publicly supported medical assistance, OR
  • Identify as race or ethnic minority
  • Has capacity for informed consent

Exclusion Criteria

  • Untreated, current major depressive disorder
  • History of bipolar or psychosis
  • Active substance abuse or drug abuse
  • Excessive daytime sleepiness
  • Seizure within the past 1 year
  • Main sleep period outside of 8pm - 11am
  • Regular nightshift work
  • Untreated, previously diagnosed moderate to severe sleep apnea
  • Severe medical condition, which may require hospitalizations over the next 6 months
  • Active suicidal ideation, if elicited passively during screening

Outcomes

Primary Outcomes

Insomnia severity index, ISI

Time Frame: 3 months

The Insomnia Severity Index is a 7-item self-report questionnaire assessing the nature, severity, and impact of insomnia in the last month. A 5-point Likert scale is used to rate each item (e.g., 0 = no problem; 4 = very severe problem), yielding a total score ranging from 0 to 28. The total score is interpreted as follows: absence of insomnia (0-7); sub-threshold insomnia (8-14); moderate insomnia (15-21); and severe insomnia (22-28).

Secondary Outcomes

  • Quality of Life and Symptoms - Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health(3-months)
  • Patient Health Questionnaire for depression (PHQ-8)(3-months)
  • Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Impairment, 8a(3-months)
  • Insomnia severity index, ISI(6- and 12-months)
  • Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance, 8b(3-months)
  • Diary-reported sleep efficiency(3-months)
  • Quality of Life and Symptoms - Generic-quality of life(3-months)
  • Generalized Anxiety Disorder (GAD-7)(3-months)
  • Diary reported sleep duration(3-months)
  • Number of participants with hypnotic use self-reported from the sleep diary(3-months)

Study Sites (1)

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