Clinical study on the treatment of gastroesophageal reflux cough by the reverse embedding method of tongdu xuanfei
- Conditions
- Gastroesophageal reflux cough
- Registration Number
- ITMCTR2100004898
- Lead Sponsor
- anjing Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1.Diagnostic criteria:
In this study, the relevant diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Caughing (2015) and the Guidelines for the Diagnosis and Management of gastroesophageal reflux disease were as follows:
(1)Chronic cough, mainly in the daytime, worsened after eating, lasting for more than 8 weeks, and no obvious lesions on chest CT;
(2)Coughing is related to eating, such as coughing after meals or eating;
(3)Accompanied by acid reflux, belching, burning sensation behind the sternum and other symptoms;
(4)The changes of reflux inflammation of esophagus were observed by endoscopy;
(5)Cut-variant asthma, eosinophilic bronchitis, postnasal drip syndrome and other diseases were excluded. Items (1) and (5) above, together with any of the other items, are required to be clinically diagnosed as GERC.
2.
(1)It meets the above diagnostic criteria;
(2)Aged 18 to 70 years, gender is not limited;
(3)No exposure history of COVID-19 within 14 days;
(4)No history of digestive system surgery;
(5)No recent treatment;
(6)Signed the informed consent.
1.Complicated with irritable bowel syndrome and other diseases of the digestive system;
2.Complicated tumor, mental disease, blood disease, serious infection, etc.;
3.Complicated with heart, liver, kidney and other serious medical diseases;
4.Unwilling to accept acupuncture treatment or have a history of needle sickness;
5.People with a history of drug allergy;
6.Severe anxiety, depression and obvious suicidal tendency;
7.Pregnant or lactating women.
Any of the above items should be excluded.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cough symptom score sheet;Lower esophageal sphincter pressure;Reflux disease diagnostic questionnaire score;
- Secondary Outcome Measures
Name Time Method eicester Cough Questionnaire;