Video-assisted Thoracoscopic Thymectomy Versus Subxiphoid Procedure
Not Applicable
Recruiting
- Conditions
- Thymectomy
- Interventions
- Procedure: VATS surgery procedureProcedure: Subxiphoid surgery procedure
- Registration Number
- NCT04223466
- Lead Sponsor
- The Second Hospital of Shandong University
- Brief Summary
Surgerys used in thymectomy for myasthenia gravis and anterior mediastinal tumours have become much less invasive in recent years. In our study, the surgical technique which resected the thymus below the xiphoid process and the technique which was regarded as conventional video- assisted thoracoscopic surgery (VATS) thymectomy was compared.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Thymoma with or without myasthenia gravis；
- Generalized myasthenia gravis not sensitive to conservative medicine treatment;
- Good cardiopulmonary function.
Exclusion Criteria
- Cardiopulmonary function can't bear surgery;
- Generalized myasthenia gravis with MuSK(+).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description VATS group VATS surgery procedure Video-assisted thoracoscopic thymectomy through chest wall. Subxiphoid group Subxiphoid surgery procedure Subxiphoid procedure for thymectomy.
- Primary Outcome Measures
Name Time Method Operation time one day in minutes
Visual Analogue Scale of postoperative pain within 3 days in score
Duration of drainage with 7 days in days
The amount of blood loss one day in milliliter
Duration of hospital stay with 7 days in days
- Secondary Outcome Measures
Name Time Method Complete remission rates 5 years Complete remission rates after 5 year follow-up of thymectomy for myasthenia gravis
Recurrence rate 5 years Recurrence rate after 5 year follow-up of thymectomy for thymoma
Overall survival within 10 years Overall survival in rate
Trial Locations
- Locations (1)
Yunpeng
🇨🇳Jinan, Shandong, China