Effect of Uterine Manipulator on Recurrence and Mortality of Endometrial Cancer
- Conditions
- Endometrial Cancer
- Interventions
- Device: UTERINE MANIPULATOR
- Registration Number
- NCT02943811
- Lead Sponsor
- Università degli Studi dell'Insubria
- Brief Summary
The investigators sought to retrospectively assess whether the use of a intrauterine device to manipulate the uterus does affect the long-term oncologic outcomes of patients operated by laparoscopy for endometrial cancer
- Detailed Description
The investigators retrospectively collected data regarding patients who received operation by laparoscopy for presumed clinical stage I endometrial cancer. The subjects were then stratified according to the use or not of the uterine manipulator. The investigators also considered the actual type of manipulator used. Then disease-free, disease-specific and overall survival were evaluated, as well as all the possible factors associated with prognosis.
Data were retrieved from specifically designed research quality internal surgical databases, prospectively updated by trained residents on a regular basis, in order to capture all the possible surgical and follow-up data.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 951
- Clinical stage I endometrial cancer
- Laparoscopic operation
- post-operative oncologic follow-up < 12 months
- extra-uterine evidence of disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description MANIPULATOR UTERINE MANIPULATOR Patients who were operated for endometrial cancer by laparoscopy with the use of a uterine manipulator
- Primary Outcome Measures
Name Time Method Disease recurrence 4 years Relapse of disease during follow-up
- Secondary Outcome Measures
Name Time Method disease specific survival 4 years Kaplan Meyer curves and Log-rank test to explore disease-specific survival
overall survival 4 years Kaplan Meyer curves and Log-rank test to explore overall survival