Effect of Uterine Manipulator on Recurrence and Mortality of Endometrial Cancer: a Multi-centric Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 951
- 主要终点
- Disease recurrence
研究概览
简要总结
The investigators sought to retrospectively assess whether the use of a intrauterine device to manipulate the uterus does affect the long-term oncologic outcomes of patients operated by laparoscopy for endometrial cancer
详细描述
The investigators retrospectively collected data regarding patients who received operation by laparoscopy for presumed clinical stage I endometrial cancer. The subjects were then stratified according to the use or not of the uterine manipulator. The investigators also considered the actual type of manipulator used. Then disease-free, disease-specific and overall survival were evaluated, as well as all the possible factors associated with prognosis.
Data were retrieved from specifically designed research quality internal surgical databases, prospectively updated by trained residents on a regular basis, in order to capture all the possible surgical and follow-up data.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Clinical stage I endometrial cancer
- •Laparoscopic operation
排除标准
- •post-operative oncologic follow-up < 12 months
- •extra-uterine evidence of disease
结局指标
主要结局
Disease recurrence
时间窗: 4 years
Relapse of disease during follow-up
次要结局
- disease specific survival(4 years)
- overall survival(4 years)
研究者
Stefano Uccella
Doctor
Università degli Studi dell'Insubria